Despite being initially set in Miami, at the end of the fourth season, it was relocated to Los Angeles, and many of the characters followed along. The show premiered on July 22, 2003, and concluded on March 3, 2010, with the 100th episode. Unlike most medical dramas, Nip/Tuck used serial storytelling and often had story arcs spanning multiple seasons for example, seasons two and three focused on a serial rapist known as The Carver, who often mutilates his victims' faces, leading McNamara/Troy to provide pro bono surgery to the victims. With the exception of the pilot, each episode of the series is named after one of the patients scheduled to receive plastic surgery. Liz Cruz, Christian's many sexual partners, and Sean's family.

Focus is also given to McNamara/Troy's anesthesiologist Dr. Each episode features graphic, partial depictions of the plastic surgeries on one or more patients, as well as developments in the doctors' personal lives. Christian Troy (portrayed by Dylan Walsh and Julian McMahon, respectively). The series, which also incorporates elements of crime drama, black comedy, family drama, satire, and psychological thriller, focuses on 'McNamara/Troy', a cutting-edge, controversial plastic surgery center, and follows the personal and professional lives of its founders Dr. Nip/Tuck is an American medical drama television series created by Ryan Murphy that aired on FX in the United States from July 22, 2003, to March 3, 2010.

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